Opioids: Harm Reduction & Overdose Prevention


This information is for people who use opioids. It focuses on staying safer, reducing overdose risk, and protecting your health.


Overdose Risk

Opioids slow breathing. Overdose can happen quickly, especially with:

  • New or unknown supply
  • Reduced tolerance
  • Mixing with alcohol or benzodiazepines
  • Using alone

Safer Use Tips

  • Carry naloxone and tell others where it is
  • Test supply when possible (fentanyl/xylazine strips)
  • Start with a small amount, especially after a break
  • Avoid mixing with alcohol or benzos
  • Try not to use alone—use with someone you trust or an overdose prevention line

Signs of Overdose

  • Slow or stopped breathing
  • Unresponsive or unconscious
  • Blue or gray lips or fingertips
  • Gurgling or choking sounds

Call emergency services and give naloxone if available.

After Naloxone

  • Naloxone can wear off before opioids do
  • Stay with the person
  • Don’t let them use more
  • Get medical help if possible

You deserve to stay alive.

See more Harm Reduction articles here.


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